It is quiet here in the PK lab at the BMC. I am all alone. My models are running at the speed of light because I am the only user of the PK/PD cluster.
Here I present the visual predictive checks (VPC) for zidovudine (AZT) and nevirapine (NVP) created using the PSN platform. "Dear diary" moments.
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Just look at the pretty pictures and go "Wow. These look really great!".
The prediction intervals are the confidence intervals for the simulated dependent variables (DV), based on the model. Here is used a three compartment model with transit absorption compartments and intra-individual variability on the number of transit compartments, the mean residence time and the central volume of distribution. The error model included a breakpoint between the magnitude of the weighted residuals for absorption and disposition phases.
Well, you asked! Did it help?
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